2002년 국제학술지 게재논문. 한의학박사 김지훈

통증은 예나 지금이나 환자들을 가장 괴롭게 하는 증상중의 하나입니다. 그중에서도 교통사고 등의 각종 사고 및 외상 등으로 인한 신경병증성 통증은 매우 심각한 통증을 보입니다.

이러한 신경병증성 통증에 있어서 침치료를 통하여 신경병증성 통증의 증상중에 하나인 이질통(가벼운 비통증성자극에도 극심한 통증으로 느끼는 현상)에 효과가 있음을 보여준 논문입니다.

역시 저명한 국제 학술지에 실려있습니다.

Neurosci Lett. 2002 Mar 1;320(1-2):49-52.

Effects of electroacupuncture on the mechanical allodynia in the rat model of neuropathic pain.

Hwang BG, Min BI, Kim JH, Na HS, Park DS.

Department of East-West Medicine, Graduate School, Kyung Hee University, Seoul, South Korea.

The analgesic effects of acupuncture on the mechanical allodynia in the rat model of neuropathic pain have not yet been studied. The aim of the present study is: first, to determine if electroacupuncture (EA) or morphine attenuates the mechanical allodynia; and secondly, to examine if the EA effect may be mediated by endogenous opioids. To produce neuropathic pain, the right superior caudal trunk was resected between the S3 and S4 spinal nerves. Twenty-one days after the neuropathic surgery, low frequency EA stimulation (2 Hz, 0.3 ms, 0.07 mA) delivered to Houxi (S13) for 30 min relieved significantly the signs of mechanical allodynia. Intraperitoneal (i.p.) morphine (0.5 or 1.5 mg/kg) also relieved the signs of mechanical allodynia in a dose-dependent manner. In addition, the antiallodynic effect of Houxi EA was blocked by pretreatment with naloxone (2 mg/kg, i.p.). However, combined application of EA and morphine did not show an obvious synergistic effect. These results suggest that low frequency EA or morphine can relieve the mechanical allodynia signs and the EA effect can be mediated by endogenous opioid systems.

-----------------------------------------------------------------
◎ 구 홈페이지에서 이전된 글입니다.
-----------------------------------------------------------------